New Medicine(Chinese name: Yixue Xinzhi Zazhi)
Sponsor:Zhongnan Hospital of Wuhan University
Working Committee of Medical Science & Technology,
Hubei Committee of Chinese Peasants and Workers Democratic Party
Organizer:Center for Evidence-Based and Translational Medicine,
Wuhan University
Information:BimonthlyISSN 1004-5511CN 42-1220/RCODEN YXIIAF
Wechat:Search"武汉大学循证与转化医学中心"
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Progress in the development of ovarian cancer organoids and their application in drug testing
DOI:10.12173/j.issn.1004-5511.202105038
Ovarian cancer has been one of the most malignant cancers in women, with the incidence increasing year by year. The most universally used preclinical models, cancer cell lines, and mouse models have many drawbacks making them fundamentally limited in representing the real characteristics of cancer. Numerous anticancer drugs developed from screening cancer cell lines and mouse models have failed in
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Research on the application and development trend of blockchain technology to patents in the field of medical and health information
DOI:10.12173/j.issn.1004-5511.202102011
Objective To analyze the patents of blockchain technology in the field of medical and health information worldwide. Methods Based on the blockchain patent data in this field from 2009 to 2020 in the Orbit patent database, both patent and social network analysis were used to analyze the application situation, distribution of research and development institu-tions, key areas and cooperat
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Report of 2 cases of diabetes insipidus and pituitary stalk thickening
DOI:10.12173/j.issn.1004-5511.202010023
To analyze the clinical data of 2 patients with diabetes insipidus (DI) who had pituitary stalk thickening (PST) and review the literature. The 2 patients were a 16-year-old boy and a 13-year-old girl who presented with complaints of thirst and polyuria. Both pituitary MRIs suggested PST. The boy had central diabetes insipidus (CDI), while the girl had both CDI and anterior pituitary dysfunction (
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Progress in research into exosomes in breast cancer microenvironment
DOI:10.12173/j.issn.1004-5511.202009026
Breast cancer is a major disease affecting women's health. The tumor microenvironment is a complex and dynamically changing group of cells and non-cellular components involved in the process of tumor progression. At present, more and more evidence indicates that exosomes in the breast cancer microenvironment can participate in the occurrence, development and prognosis of breast cancer by regul
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Differentially expressed miRNAs in Luminal and Basal-like breast cancer
DOI:10.12173/j.issn.1004-5511.202101059
Objective To analysis differences in differentially expressed microRNAs (miRNAs) between luminal and basal-like breast cancer, and to explore the relationship between the expression level and the prognosis of luminal and basal-like breast cancer.Methods The miRNAs microarray datasets GSE81000 and GSE40267 which included the luminal and basal-like breast cancer patients were downloaded
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A study on smoking and secondhand smoke exposure among people at high risk of chronic diseases
Fang ZHOU , Qing-Qing JIANG , Tian-Tian WANG , Shi-Yi CAO 2021, 31(4): 243-248
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Analysis of the burden of gastrointestinal diseases between 1990 and 2017 in China
Lu-Yao LI , Zhong-Li ZHENG , Xin-Li GAN , Xing-Pei GUO , Hao ZI , Zhi-Yuan JIAN , Xue-Qun REN , Xian-Tao ZENG 2021, 31(4): 249-256
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Research on the application and development trend of blockchain technology to patents in the field of medical and health information
Ji-Bin XIN , Li-Jun WU , Xin YANG , Man WANG 2021, 31(4): 257-265
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Evidence-based clinical practice guideline for chemoprophylaxis, diagnosis, treat-ments, and discharge management of COVID-19: an evidence evaluation (2)
Yong-Bo WANG , Li-Sha LUO , Li-Ye LU , Jia-Ao LOU , Ying-Hui JIN 2021, 31(4): 266-278
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Progress in the development of ovarian cancer organoids and their application in drug testing
Dong CHEN , Yan-Fang SHI , Yu-Chen LIU 2021, 31(4): 279-284
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Recent advances in the application of patient-derived tumor xenograft models in prostate cancer
Jian-Li DUAN , Zheng CHEN , Yu-Zhuo WANG 2021, 31(4): 285-293
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The progress of research into the role of D-lactic acid in the diagnosis of periprosthetic joint infection
Zhi-Zhuo LI , Li-Jun SHI , Wei SUN 2021, 31(4): 294-298
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Advances in the prevalence of peripheral artery disease
Qian-Nan ZHAO , Xiang-Hua FANG 2021, 31(4): 299-306
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A literature review and case report of severe hepatitis caused by the G6PD gene c.1478G>A muta-tion
Jian LIU , Yan-Jun WANG , Shun-Jun XIONG , Bing-Yan HE , You-Ping DENG , Dong-Chi ZHAO 2021, 31(4): 307-310
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Four cases of transcatheter aortic valve implatation
Yin-Xia HUANG , Min LI , Xin-Hao CHEN , Xing-You LIU , Ji-Gang HE 2021, 31(4): 311-315
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Application of the TBL teaching model in microsurgery technology training which provides standardize training for surgical residents
Xian-Shun HAN , Qian-Jin ZHENG , Xiang HU , Sheng-Xiang TAO 2021, 31(4): 316-322
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