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目的 分析武汉某高校学生肠道菌群多样性,探讨影响肠道菌群多样性的因素。方法 选取武汉某高校学生的粪便样品作为研究对象,应用Illumina Miseq平台进行高通量测序技术,检测大学生肠道菌群的多样性及影响因素。结果 ①大学生肠道菌群存在α多样性,但α多样性不受吸烟、运动、不同频次摄入果蔬、白肉、红肉、腌熏制品等因素影响(P>0.05);②吸烟使肠道菌群中放线菌门、双歧杆菌属、帕拉普菌属、氨基酸球菌属丰度显著升高(P<0.05);③运动使肠道菌群中毛螺旋菌属、帕拉普菌属丰度升高(P<0.05);④高频次食用果蔬使大学生肠道菌群中毛螺菌属丰度升高;低频次食用白肉使肠道菌群中芽孢杆菌属、微单胞菌属丰度升高;高频次食用红肉使丁酸弧菌属、脱硫弧菌属丰度降低,而志贺菌属丰度升高;高频次食用腌熏制品使肠道菌群中瘤胃球菌属、醋杆菌属丰度升高(P<0.05)。结论 吸烟、运动及不同频次摄入果蔬、白肉、红肉、腌熏制品等均可影响肠道菌群的数量和种类。

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