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HomeArticlesVol 31,2021 No.1Detail

Functions of CircRNAs in osteogenic differentiation

Published on Feb. 20, 2021Total Views: 4004 timesTotal Downloads: 2101 timesDownloadMobile

Author: Hui-Xian DONG 1, 2 Jia-Lin ZHONG 1, 2 Qian-Zhou JIANG 1, 2

Affiliation: 1. Department of Endodontics, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510182, China 2. Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou 510182, China

Keywords: CircRNAs Osteogenesis Differentiation Regulation

DOI: 10.12173/j.issn.1004-5511.2021.01.04

Reference: Dong HX, Zhong JL, Jiang QZ. Functions of CircRNAs in osteogenic differentiation[J]. Yixue Xinzhi Zhazhi, 2021, 31(1): 23-32. DOI: 10.12173/j.issn.1004-5511.2021.01.04.[Article in Chinese]

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Abstract

CircRNAs are a special class of non-coding RNA (ncRNA) molecules. They have a closed circular structure and are formed by reverse splicing by non-classical splicing methods. They coexist in highly differentiated eukaryotes. More and more studies have shown that CircRNAs would change during osteogenic differentiation. This paper introduces the role of CircRNAs in tissue cell osteogenic differentiation, and reviews the current research status of the targets and signaling pathways of CircRNAs during osteogenic differentiation.

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