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Research on the promotion of implementation of clinical practice guidelines(III): conceptual level de-sign of a knowledge graph for clinical guidelines for Traditional Chinese Medicine/Integrated Tradi-tional Chinese and Western Medicine

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Author: GUO Jing 1 SI Yibei 2 WANG Yongbo 3 GAO Kuang 4 HUANG Qiao 3 LI Xuhui 3 YAN Siyu 3 WANG Jiaying 5 ZHANG Rong 6 REN Xiangying 7 JIN Yinghui 3 SHANG Hongcai 8

Affiliation: 1. Acupuncture and Rehabilitation Department, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China 2. The Second Clinical College, Wuhan University, Wuhan 430071, China 3. Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China 4. School of Computer Science, Wuhan University, Wuhan 430072, China 5. National Drug Clinical Trials Institution, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214000, Jiangsu Province, China 6. Neurosurgery II ward, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei Province, China 7. School of Nursing and Health, Henan University, Kaifeng 475000, Henan Province, China 8. Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China

Keywords: Traditional Chinese Medicine Integrated Traditional Chinese and Western Medicine Clinical guideline Knowledge graph


Reference:Guo J, Si YB, Wang YB, Gao K, Huang Q, Li XH, Yan SY, Wang JY, Zhang R, Ren XY, Jin YH, Shang HC. Research on the promotion of implementation of clinical practice guidelines (Ⅲ): conceptual level design of a knowledge graph for clinical guidelines for Traditional Chinese Medicine/Integrated Traditional Chinese and Western Medicine[J]. Yixue Xinzhi Zazhi, 2022, 32(1): 2-9. DOI: 10.12173/j.issn.1004-5511.202111057.[Article in Chinese]

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The significance of the existence of clinical practice guidelines lies in their implementation, however, there are still many problems in the implementation of guidelines and bottlenecks in the translation of clinical evidence. The introduction of knowledge graph technology provides a solid foundation for guideline intel-ligence and a good tool for solving guideline implementation problems. The combined Traditional Chinese Medi-cine (TCM)/ Integrated Traditional Chinese and Western Medicine (IM) reflect the characteristics of the healthcare system in China. Using the current status of TCM/IM diagnosis and treatment of cardiovascular diseases and the current problems in the application of TCM/IM guidelines for cardiovascular diseases, this study defined the objectives of constructing a knowledge graph for TCM/IM clinical guidelines for cardiovascular diseases, and accordingly designed a knowledge graph framework for TCM/IM clinical guidelines that is con-sistent with professional knowledge and practical application. We analyzed the scope of the guidelines, ar-ranged their content and summarized their knowledge structure. We then established concept structure tables and entity semantic relationship tables. The design of the knowledge graph framework for TCM/IM guidelines proposed in this paper provides a basis for the digitization and communication of guidelines, and is conducive to promoting their implementation and dissemination. 

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1. Institute of Medicine (US) Committee on Standards for Developing Trustworthy Clinical Practice Guidelines. Clinical practice guidelines we can trust[M]. Washington (DC): National Academies Press, 2011. DOI: 10.17226/ 13058.

2. Hesketh T, Zhu WX. Health in China. Traditional Chinese medicine: one country, two systems[J]. BMJ, 1997, 315(7100): 115-117. DOI: 10.1136/bmj.315.7100.115.

3. Chen Y, Wang C, Shang H, et al. Clinical practice guidelines in China[J]. BMJ, 2018, 360: j5158. DOI: 10.1136/bmj.j5158.

4. 靳英辉, 邓通, 曾宪涛, 等. 临床实践指南制订方法——指南的实施与转化[J]. 中国循证心血管医学杂志, 2019, 11(9): 1040-1042, 1046. [Jin YH, Deng T, Zeng XT, et al. Methodology for clinical practice guide-lines--implementation and transformation of guidelines[J]. Chinese Journal of Evidence-Based Cardio-vascular Medicine, 2019, 11(9): 1040-1042, 1046.] DOI: 10.3969/j.issn.1674-4055.2019.09.03.

5. 董斐, 刘建平. 从“经验”到“证据”:循证医学促进中医药传承创新发展[J]. 南京中医药大学学报, 2021, 37(5): 642-647. [Dong F, Liu JP. From "Exprerience" to "evidence": evidence-based medicine facilitates the in-teritance and innovation of traditional Chinese medicine[J]. Journal of Nanjing University of Traditional Chinese Medicine, 2021, 37(5): 642-647.] DOI: 10.14148/j.issn.1672- 0482.2021.0642.

6. 尹梓名, 吕旭东, 段会龙. 基于临床指南的决策支持系统[J]. 中国医疗器械信息, 2015, 21(3): 1-5, 23..[Yin ZM, Lyu XD, Duan JL. Guideline-based clinical decision support system[J]. China Medical Device Information, 2015, 21(3): 1-5, 23.] DOI: 10.15971/j.cnki.cmdi.2015.03.001.

7. 陈耀龙, 史乾灵, 赵俊强, 等. 从知到行:跨越指南理论与实践的鸿沟[J]. 协和医学杂志, 2020, 11(6): 746-753. [Chen YL, Shi QL, Zhao JQ, et al. From knowledge to action: bridging the gap between theory and practice in clinical practice guidelines[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(6): 746-753.] DOI: 10.3969/j.issn.1674-9081.2020.06.020.

8. Murdoch TB, Detsky AS. The inevitable application of big data to health care[J]. JAMA, 2013, 309(13): 1351-1352.DOI: 10.1001/jama.2013.393.

9. He J, Baxter SL, Xu J, et al. The practical implementation of artificial intelligence technologies in medi-cine[J]. Nat Med, 2019, 25(1): 30-36. DOI: 10.1038/s41591-018-0307-0. 

10.侯梦薇, 卫荣, 陆亮, 等. 知识图谱研究综述及其在医疗领域的应用[J]. 计算机研究与发展, 2018, 55(12): 2587-2599. [Hou MW, Wei R, Lu L, et al. Research review of knowledge graph and its application in medical domain[J]. Journal of Computer Research and Development, 2018, 55(12): 2587-2599.] DOI: 10.7544/issn1000-1239.2018.20180623.

11.孙华君, 李海燕, 聂莹, 等. 知识图谱及其在中医药领域应用研究进展[J]. 世界科学技术-中医药现代化, 2020, 22(6): 1969-1974. [Sun HJ, Li HY, Nie Y, et al. Research progress on knowledge graphs and their application in traditional Chinese medicine[J]. World Science and Technology-Modernization of Traditional Chinese Medicine, 2020, 22(6): 1969-1974.] DOI: 10.11842/wst.2019 0429007.

12.中华中医药学会心血管病分会. 冠心病稳定型心绞痛中医诊疗指南[J]. 中医杂志, 2019, 60(21): 1880-1890. [China Association of Chinese Medicine Cardiovascular Disease Section. Guidelines of the traditonal Chinese medicine for stable angina pectoris in coronary artery disease[J]. Journal of Traditional Chinese Medi-cine, 2019, 60(21): 1880-1890.] DOI: 10.13288/j.11-2166/r.2019.21.015.

13.中华中医药学会心血管病分会. 冠心病心绞痛介入前后中医诊疗指南[J]. 中国实验方剂学杂志, 2018, 24(15): 4-6. [China Association of Chinese Medicine Cardiovascular Disease Section. Guidelines of the traditonal Chinese medicine for before and after coronary heart disease angina pectoris intervention treat-ment[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2018, 24(15): 4-6.] DOI: 10.13422/j.cnki.syfjx.20184101.

14.中国医师协会中西医结合医师分会, 中国中西医结合学会心血管病专业委员会, 中国中西医结合学会重症医学专业委员会, 等. 急性心肌梗死中西医结合诊疗指南[J]. 中国中西医结合杂志, 2018, 38(3): 272-284. [Doctor Society of integrative Medicine of Chinese Medical Doctor Association, Specialist Committee on Cardiovascu-lar Disease of Chinese Integrative Medicine Association, Committee of Intensive Care Medicine of Chinese Association of Integrative Medicine, et al. Guidelines for the integrated traditional Chinese and Western medicine treatment of acute myocardial infarction[J]. Chinese Journal of Integrated Tra-ditional and Western Medicine, 2018, 38(3): 272-284.] DOI: 10.7661/j.cjim.20180119.038.

15.世界中医药联合会心血管病专业委员会, 中国中西医结合学会心血管病专业委员会, 中华中医药学会介入心脏病学会, 等. 冠状动脉血运重建术后心绞痛中西医结合诊疗指南[J]. 中国中西医结合杂志, 2020, 40(11): 1298-1307. [Specialist Committee on Cardiovascular Disease of World Federation of Chinese Medicine, Specialist Committee on Cardiovascular Disease of Chinese Integrative Medicine Association, China Association of Chinese Medicine Interventional Cardiology Society, et al. Guidelines for the integrated treatment of angina pectoris after coronary revascularization[J]. Chinese Journal of Integrated Traditional and Western Medicine, 2020, 40(11): 1298-1307.] DOI: 10.7661/j.cjim.20200917.181.

16.OMAHA Schema[EB/OL]. (2021-11-12) [Access on 2021-12-08]. http://wiki.omaha.org.cn/display/KG/OMAHA+Schema.

17.何丽云, 李新龙, 刘岩, 等. 中医师辨证论治知识图谱构建的思路与方法[J]. 中医杂志, 2017, 58(19): 1650-1653. [He LY, Li XL, Liu Y, et al. Ideas and methods for the construction of a knowledge graph for the identi-fication and treatment of Chinese medicine practitioners[J]. Journal of Traditional Chinese Medicine, 2017, 58(19): 1650-1653.] DOI: 10.13288/j.11-2166/r.2017.19.008.

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